Determining your patients' HRR mutation status

Specific HRR gene testing should include BRCA1/2, ATM, PALB2, and CHEK2 genes³.

By identifying patients with HRR mutations at metastatic disease diagnosis, you can learn more about their disease³

Contact a Janssen Representative to learn more about HRR testing, and for more information about where and how to test

ATM: Ataxia-telangiectasia mutated

BRCA1: Breast cancer gene 1

BRCA2: Breast cancer gene 2

CHEK2: Checkpoint kinase 2

HRR: Homologous recombination repair

PALB2: Partner and localizer of BRCA2

REFERENCE: Scott RJ, Mehta A, Macedo GS, et al. Oncotarget 2021;12(16):1600–1614. ↵